Reliability and validity of cross­culturally adapted oral health­related quality­of­Life instruments for Brazilian children and adolescents: a systematic review.

OBJECTIVE: This systematic review aimed to review the reliability and validity of oral health-related quality of life (OHRQoL) questionnaires for Brazilian children and adolescents. Also, the cross-cultural adaptation was evaluated. METHODS: This systematic review is registered in PROSPERO (CRD42022300018) and was performed based on the COSMIN guideline. Electronic searches were performed in the PubMed/MEDLINE, Web of Science, Lilacs, BVS (BIREME), Scielo, and Embase databases until March 2023 by two independent reviewers. There was no restriction on time or language. The following studies were included: validation studies and cross-cultural adaptation of OHRQoL instruments into Brazilian Portuguese; studies that evaluated the measurement properties of OHRQoL questionnaires in children and adolescents and that reported at least one of the measurement properties: reliability, internal consistency, error measurement, content validity, construct validity, criterion validity, discriminant validity, and/or convergent validity. The following were excluded: studies of systematic reviews of OHRQoL measures; studies reporting OHRQoL assessment through instruments; construction (development) and validation of a new instrument; questionnaires that had a single item; and validation for Portuguese from Portugal. The cross-cultural adaptation process and psychometrics of the included studies were verified. RESULTS: 6556 articles were identified, and 19 manuscripts were included. All studies were conducted in Brazil, and the age of the participants ranged from 2 to 15.42 years old. Sixteen articles presented the cross-cultural validation steps. Cronbach's alpha of the revised instruments ranged from 0.59 to 0.86. CONCLUSIONS: It can be concluded that most studies provided information and evidence regarding validity, reliability, translation, and cultural adaptation.

Psychometric assessment of oral health-related quality of life questionnaires cross-culturally adapted for use in Brazilian adults - a systematic review.

OBJECTIVE: This study aimed to review the psychometric properties of oral health-related quality of life (OHRQoL) questionnaires for the Brazilian adult population. METHODS: A systematic review was performed based on the COSMIN guidelines (PROSPERO CRD42022300018). The studies were obtained through electronic searches in the PubMed/MEDLINE, Web of Science, Lilacs, VHL (BIREME), SciELO, and Embase databases. RESULTS: The search was performed in December 2022. Articles on OHRQoL that reported the cross-cultural adaptation of instruments into Portuguese (Brazil) and evaluated the psychometric properties of measuring instruments in adult patients were included. Those about the development of a novel instrument and participants under 18 years of age were excluded. Information was collected on the country, type of instrument validated, psychometric tests, and adaptation process. The certainty of the evidence was assessed using GRADEpro program. The search returned 6,556 articles, and 14 were considered for this review. However, two studies did not report the cross-cultural adaptation process. Content validity, internal consistency, criterion validity, construct validity, reliability, general discriminant validity, Cronbach's alpha value, and general intraclass correlation coefficient value were confirmed in 12 studies. Cronbach's alpha ranged from 0.69 to 0.96. The certainty of the evidence was considered moderate and low. This study has some limitations, such as the lack of information in some reviewed studies, the unavailability of Brazilian instruments, and absence of longitudinal validation of some instruments. CONCLUSIONS: In conclusion, there are 14 OHRQoL instruments adapted for Brazilian adults that can be used with caution by researchers and clinicians, since they presented moderate to low certainty of the evidence.

Anaerobic adhesives effect on counter-torque of abutment screws on implants with external hexagon and conical connections: An in vitro study.

BACKGROUND: Abutment screw loosening is a common complication of implant supported prostheses, especially for single crowns. In engineering, anaerobic adhesives (AA) are used to provide chemical locking between screw surfaces, but their application in implantology remains unclear. PURPOSE: The purpose of this article is to evaluate, in vitro, the effect of AA on counter-torque of abutment screws for cemented prosthesis on dental implants with external hexagon connection (EHC) and conical connection (CC). MATERIALS AND METHODS: Sample was composed by 60 specimens, 30 dental implants with EHC and 30 with CC. Abutments (transmucosal 3 mm straight universal abutment) were installed without AA (control group) or with application of AA with two different adhesive strength: medium strength (LOCTITE® 242) and high strength (LOCTITE® 277). The specimens were subjected to mechanical cycling at 37°C, with a load setting of 133 N, a 1.3 Hz frequency, and 1 200 000 cycles. The abutments were removed, and the counter-torque values were registered. Screws and implants were inspected using a stereomicroscope to verify the presence of residual adhesive and damage the internal structures. The data were analyzed using descriptive statistics and comparison tests (p < 0.05). RESULTS: Comparing to the torque of installation, the medium strength AA kept the counter-torque values for CC implants and the high strength AA kept the counter-torque for EHC implants and increased for CC implants. In the intergroup comparisons, control group presented significantly lower counter-torque values than other groups, both for EHC and CC implants. High strength AA presented similar results to medium strength AA in the EHC implants, but in the CC implants presented higher counter-torque values. Damage in threads was more frequent in the groups that received high strength AA. CONCLUSION: The use of AA increased the counter-torque of abutment screws, both in implants with EHC and CC.

Psychometric assessment of oral health-related quality of life questionnaires cross-culturally adapted for use in Brazilian adults - a systematic review / Avaliação psicométrica de questionários de qualidade de vida relacionada à saúde bucal adaptados culturalmente para uso em adultos brasileiros - uma revisão sistemática

ABSTRACT Objective: This study aimed to review the psychometric properties of oral health-related quality of life (OHRQoL) questionnaires for the Brazilian adult population. Methods: A systematic review was performed based on the COSMIN guidelines (PROSPERO CRD42022300018). The studies were obtained through electronic searches in the PubMed/MEDLINE, Web of Science, Lilacs, VHL (BIREME), SciELO, and Embase databases. Results: The search was performed in December 2022. Articles on OHRQoL that reported the cross-cultural adaptation of instruments into Portuguese (Brazil) and evaluated the psychometric properties of measuring instruments in adult patients were included. Those about the development of a novel instrument and participants under 18 years of age were excluded. Information was collected on the country, type of instrument validated, psychometric tests, and adaptation process. The certainty of the evidence was assessed using GRADEpro program. The search returned 6,556 articles, and 14 were considered for this review. However, two studies did not report the cross-cultural adaptation process. Content validity, internal consistency, criterion validity, construct validity, reliability, general discriminant validity, Cronbach's alpha value, and general intraclass correlation coefficient value were confirmed in 12 studies. Cronbach's alpha ranged from 0.69 to 0.96. The certainty of the evidence was considered moderate and low. This study has some limitations, such as the lack of information in some reviewed studies, the unavailability of Brazilian instruments, and absence of longitudinal validation of some instruments. Conclusions: In conclusion, there are 14 OHRQoL instruments adapted for Brazilian adults that can be used with caution by researchers and clinicians, since they presented moderate to low certainty of the evidence.

RESUMO Objetivo: Este estudo teve como objetivo revisar as propriedades psicométricas dos questionários de qualidade de vida relacionada à saúde bucal (OHRQoL) para a população adulta brasileira. Métodos: Foi realizada uma revisão sistemática com base nas diretrizes Consensus-based standards for the selection of health measurement instruments - COSMIN (International Prospective Register of Systematic Reviews - PROSPERO CRD42022300018). Os estudos foram obtidos por meio de buscas eletrônicas nas bases de dados United States National Library of Medicine (PubMed)/ Medical Literature Analysis and Retrieval System Online (MEDLINE), Web of Science, Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Biblioteca Virtual em Saúde - BVS (Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde - BIREME), Scientific Electronic Library Online (SciELO) e Embase. A busca foi realizada em dezembro de 2022. Foram incluídos artigos que relatavam a adaptação transcultural de instrumentos (QVRSB) para o português (Brasil) e que avaliavam as propriedades psicométricas de mensuração de instrumentos (QVRSB) em pacientes adultos. Foram excluídos aqueles sobre o desenvolvimento de um novo instrumento e com participantes menores de 18 anos. Foram coletadas informações sobre país, tipo de instrumento validado, testes psicométricos e processo de adaptação. A certeza da evidência foi avaliada usando GRADE. Resultados: A pesquisa retornou 6556 artigos, e 14 foram incluídos nesta revisão. Dois estudos não relataram o processo de adaptação transcultural. A validade de conteúdo, consistência interna, validade de critério, validade de constructo, confiabilidade, validade discriminante geral, valor alfa de Cronbach e valor geral do coeficiente de correlação intraclasse foram confirmadas em 12 estudos. O alfa de Cronbach variou de 0,69 a 0,96. A certeza da evidência foi considerada moderada e baixa. Esta pesquisa apresenta algumas limitações, como falta de informação em alguns estudos revisados; indisponibilidade de instrumentos brasileiros; ausência de validação longitudinal de alguns instrumentos. Conclusões: Em conclusão, existem 14 instrumentos de QVRSB adaptados para adultos brasileiros que podem ser utilizados com cautela por pesquisadores e clínicos, uma vez que apresentam moderada a baixa certeza de evidência.

COVID-19 em pessoas com deficiências do desenvolvimento: uma revisão de escopo / COVID-19 en personas con trastornos en el desarrollo: una revisión de alcance / COVID-19 in people with developmental disabilities: a scoping review

Resumo Objetivo Examinar a evidência emergente sobre os tipos e a frequência de deficiências do desenvolvimento na população afetada pela COVID-19, identificando formas de categorização, incidência/prevalência e comorbidades mais frequentes. Métodos Para esta revisão de escopo realizou-se busca por estudos observacionais nas bases de dados Medline (PubMed), Scopus (Elsevier), ISI Web of Science (Clarivate), Lilacs (BVS) e 'literatura cinzenta'. Como critérios de elegibilidade, os estudos deveriam apresentar resultados de ocorrência de deficiência de desenvolvimento em pessoas com COVID-19, permitindo comparação com a população em geral, ou entre os grupos de deficiências. Dois revisores independentes fizeram o mapeamento das informações utilizando um instrumento de extração de dados previamente elaborado. Outros dois pesquisadores verificaram os dados e auxiliaram na elaboração dos quadros de apresentação dos resultados. Resultados Observou-se diversidade de terminologias empregadas para categorizar as DD. As pessoas com DD e com comorbidades que representam maior risco para a COVID-19 necessitaram de internação hospitalar com maior frequência do que a população em geral. De um total de 4930 estudos, 14 foram selecionados para avaliação. Destes, 5 artigos foram estudos longitudinais. Conclusão Em pessoas com DD, a COVID-19 apresentou taxas de morbidade, letalidade e mortalidade mais altas em faixas etárias mais jovens, na população mais pobre, na população institucionalizada e que requer tecnologias de suporte de vida e cuidados especializados. A vulnerabilidade das pessoas com DD à COVID-19 depende do tipo e da gravidade da deficiência e da presença de comorbidades, evidenciando a necessidade de atenção no diagnóstico e nas medidas preventivas, como a vacinação.

Resumen Objetivo Examinar la evidencia emergente sobre los tipos y la frecuencia de trastornos en el desarrollo (TD) en la población afectada por COVID-19 e identificar formas de categorización, incidencia/prevalencia y comorbilidades más frecuentes. Métodos Para esta revisión de alcance se realizó una búsqueda de estudios observacionales en las bases de datos Medline (PubMed), Scopus (Elsevier), ISI Web of Science (Clarivate), Lilacs (BVS) y 'literatura gris'. Como criterio de elegibilidad, los estudios debían presentar resultados de casos de TD en personas con COVID-19 y permitir la comparación con la población general, o entre los grupos de trastornos. Dos revisores independientes realizaron el mapeo de la información con la utilización de un instrumento de extracción de datos previamente elaborado. Otros dos investigadores verificaron los datos y ayudaron a elaborar los cuadros de presentación de resultados. Resultados Se observó diversidad en la terminología empleada para categorizar los TD. Las personas con TD y con comorbilidades que representan mayor riesgo de COVID-19 necesitaron internación hospitalaria con mayor frecuencia que la población general. De un total de 4930 estudios, 14 fueron seleccionados para el análisis, de los cuales 5 artículos fueron estudios longitudinales. Conclusión En personas con TD, el COVID-19 presentó índices de morbilidad, letalidad y mortalidad más altos en rangos de edad más jóvenes, en la población más pobre, en la población institucionalizada y que requiere tecnologías de soporte vital y cuidados especializados. La vulnerabilidad de las personas con TD depende del tipo y gravedad del trastorno y de la presencia de comorbilidades, lo que deja en evidencia la necesidad de atención en el diagnóstico y en las medidas preventivas, como la vacunación.

Abstract Objective To examine the emerging evidence on developmental disability type and frequency in the population affected by COVID-19, identifying more frequent forms of categorization, incidence/prevalence and comorbidities. Methods For this scoping review, we searched for observational studies in the MEDLINE (PubMed), Scopus (Elsevier), ISI Web of Science (Clarivate), LILACS (VHL) and grey literature databases. As eligibility criteria, studies should present results of developmental disability (DD) occurrence in people with COVID-19, allowing comparison with the general population, or between groups of disabilities. Two independent reviewers mapped the information using a previously elaborated data extraction instrument. Two other researchers verified the data and assisted in table elaboration to present the results. Results There was a diversity of terminologies used to categorize DD. People with DD and comorbidities that represent a higher risk for COVID-19 required hospitalization more frequently than the general population. Out of a total of 4930 studies, 14 were selected for assessment. Of these, 5 articles were longitudinal studies. Conclusion In people with DD, COVID-19 had higher morbidity, lethality and mortality rates in younger age groups, in the poorest population, in the institutionalized population, requiring life support technologies and specialized care. The vulnerability of people with DD to COVID-19 depends on disease type and severity and the presence of comorbidities, highlighting the need for attention in diagnosis and preventive measures, such as vaccination.

Grafting biomaterials associated to topical glucocorticoid: effects on pre-osteoblastic cells (MC3T3-E1).

The topical glucocorticoid budesonide has been prescribed before and after sinus lift surgery as adjuvant drug treatment for maxillary sinus membrane inflammation. However, there is no study on the effects of budesonide on the regenerative process of bone grafting biomaterials. We investigated the effect of the association of budesonide with some biomaterials on the growth and differentiation capacity of pre-osteoblastic cells (MC3T3-E1 subclone 4). Xenogeneic (Bio-Oss and Bio-Gen) and synthetic hydroxyapatites (Osteogen, Bonesynth, and HAP-91) were tested in conditioned medium (1% w/v). The conditioned medium was then supplemented with budesonide (0.5% v/v). Cell viability was assessed using the MTT assay (48, 96, and 144 h), and mineralized nodules were quantified after 14 days of culture using the Alizarin Red Staining. Alkaline phosphatase activity was assessed through the release of thymolphthalein at day seven. All biomaterials showed little or no cytotoxicity. The Bio-Gen allowed significantly less growth than the control group regardless of the experimental time. Regarding differentiation potential of MC3T3-E1, the HAP-91-conditioned medium showed remarkable osteoinductive properties. In osteodifferentiation, the addition of budesonide favored the formation of mineral nodules when cells were cultured in medium conditioned with synthetic materials, whereas it weakened the mineralization potential of cells cultured in xenogeneic medium. Regardless of whether budesonide was added or not, Osteogen and Bio-Oss showed higher alkaline phosphatase activity than the other groups. Budesonide may improve bone formation when associated with synthetic biomaterials. Conversely, the presence of this glucocorticoid weakens the mineralization potential of pre-osteoblastic cells cultured with xenogeneic hydroxyapatites.

Prevalence of Mandibular Third Molars According to the Pell & Gregory and Winter Classifications.

Aim: This study aimed to evaluate the prevalence of mandibular third molar positions according to the Pell & Gregory and Winter classifications, and to verify the association between the two classification methods. Material and Methods: This cross-sectional study was conducted at dental imaging clinic, from January to March 2019. The inclusion criteria were third molars with complete rhizogenesis and the presence of the mandibular second molar. Patients under 16 years were excluded. Digital orthopantomography (panoramic radiography) radiographs of the mandibular third molars were analyzed and observed according to both Pell & Gregory and the Winter classifications, in addition to verifying if they were impacted. Data were submitted to chi-square test. Results: and StatisticsIn total, 1087 teeth were analyzed, and 1055 teeth were included in the study. The teeth were most commonly found to be in the mesioangulated position (41.8%). Higher frequency was observed for position IIB (26.4%). The prevalence of impacted teeth was 79.6%. There was a statistically significant association between the Winter classification and Pell & Gregory classification (p < 0.001). Conclusion: It was concluded that 79.6% of the mandibular third molars were impacted. The most frequent classification of teeth was position IIB, and the mesioangulated position.

Grafting biomaterials associated to topical glucocorticoid: effects on pre-osteoblastic cells (MC3T3-E1)

Abstract The topical glucocorticoid budesonide has been prescribed before and after sinus lift surgery as adjuvant drug treatment for maxillary sinus membrane inflammation. However, there is no study on the effects of budesonide on the regenerative process of bone grafting biomaterials. We investigated the effect of the association of budesonide with some biomaterials on the growth and differentiation capacity of pre-osteoblastic cells (MC3T3-E1 subclone 4). Xenogeneic (Bio-Oss and Bio-Gen) and synthetic hydroxyapatites (Osteogen, Bonesynth, and HAP-91) were tested in conditioned medium (1% w/v). The conditioned medium was then supplemented with budesonide (0.5% v/v). Cell viability was assessed using the MTT assay (48, 96, and 144 h), and mineralized nodules were quantified after 14 days of culture using the Alizarin Red Staining. Alkaline phosphatase activity was assessed through the release of thymolphthalein at day seven. All biomaterials showed little or no cytotoxicity. The Bio-Gen allowed significantly less growth than the control group regardless of the experimental time. Regarding differentiation potential of MC3T3-E1, the HAP-91-conditioned medium showed remarkable osteoinductive properties. In osteodifferentiation, the addition of budesonide favored the formation of mineral nodules when cells were cultured in medium conditioned with synthetic materials, whereas it weakened the mineralization potential of cells cultured in xenogeneic medium. Regardless of whether budesonide was added or not, Osteogen and Bio-Oss showed higher alkaline phosphatase activity than the other groups. Budesonide may improve bone formation when associated with synthetic biomaterials. Conversely, the presence of this glucocorticoid weakens the mineralization potential of pre-osteoblastic cells cultured with xenogeneic hydroxyapatites.

Degree of conversion and microhardness of resin cements photoactivated through glass ceramic.

BACKGROUND: To assess whether glass-ceramic shade, thickness and translucency affect degree of conversion (DC) and Knoop microhardness (KHN) of resin cements photoactivated using light-emitting diode (LED) or quartz-tungsten-halogen (QTH) units. MATERIAL AND METHODS: Glass-ceramic blocks were cut (2, 3 and 4mm) and sintered. For DC FT Raman spectroscopy (n=3), film specimens of cements (RelyX ARC, U200, Veneer, C&B) were obtained. For KHN test (n=3), cements were inserted in cylindrical matrix and covered by polyester strip. Specimens were photoactivated (30s) using LED or QTH according to each group: direct photoactivation (DP), interposing ceramic specimens or no photoactivation (NP). Data were analysed by ANOVA and Tukey's test, Kruskal-Wallis and Dunn's tests (p<0.05). RESULTS: Ceramic features had significant effect on DC of RelyX ARC, U200 and Veneer (p<0.0017). Light source had no effect (p=0.9512). C&B and Veneer had higher DC, followed by dual cements. NP dual cements showed the lowest DC. For KHN, ceramic shade (p=0.1717) and light source (p=0.1421) were not significant, but ceramic translucency, thickness and resin cement were significant (p=0.0001). KHN was higher for U200 followed by ARC, and lowest for Veneer. CONCLUSIONS: DC was affected by ceramic shade, translucency and thickness. KHN was dependent on ceramic translucency and thickness. Higher DC and KHN were achieved for dual-cured cements photoactivated through 2mm-thick low translucent or 3mm-thick high translucent glass-ceramic. Key words:Cementation, composite resin cements, dental curing lights, glass ceramics.

Carious lesions recurrence in children with developmental disabilities: a longitudinal study.

This study investigated the factors associated with new carious lesions in one-to five-year-old children with developmental disabilities. This was a retrospective cohort that evaluated 64 dental charts of individuals with caries or fillings in their first dental appointment. The dependent variable was the occurrence of a new carious lesion or restoration. Gender, age, mother's education, sugar consumption, oral hygiene, mouth breathing, reports of xerostomia, gingival status, use of psychotropic drugs, use of asthma drugs, history of asthma, bronchitis, reflux or seizures and having at least one sibling were covariates. Cox proportional hazards regression model was used to estimate the raw and adjusted hazard ratios with their respective 95% confidence interval. The average time that individuals remained free of dental caries/restoration was 79.49 months (95%CI: 64.37 to 92.61). Increase in sucrose consumption increased the rate of caries recurrence (HR = 1.16; 95%CI: 1.04 to 1.30). Individuals who had poor oral hygiene had higher rate of new dental caries (HR = 3.88; 95%CI: 1.22 to 12.37) compared to those with good oral hygiene. The presence of mouth breathing decreased the rate of recurrence of the disease when compared to the nasal breathing (HR = 0.32; 95%CI: 0.15 to 0.70). Oral health-related behaviors and nasal respiration influenced the rate of dental caries recurrence in individuals with developmental disabilities.

Carious lesions recurrence in children with developmental disabilities: a longitudinal study

Abstract This study investigated the factors associated with new carious lesions in one-to five-year-old children with developmental disabilities. This was a retrospective cohort that evaluated 64 dental charts of individuals with caries or fillings in their first dental appointment. The dependent variable was the occurrence of a new carious lesion or restoration. Gender, age, mother's education, sugar consumption, oral hygiene, mouth breathing, reports of xerostomia, gingival status, use of psychotropic drugs, use of asthma drugs, history of asthma, bronchitis, reflux or seizures and having at least one sibling were covariates. Cox proportional hazards regression model was used to estimate the raw and adjusted hazard ratios with their respective 95% confidence interval. The average time that individuals remained free of dental caries/restoration was 79.49 months (95%CI: 64.37 to 92.61). Increase in sucrose consumption increased the rate of caries recurrence (HR = 1.16; 95%CI: 1.04 to 1.30). Individuals who had poor oral hygiene had higher rate of new dental caries (HR = 3.88; 95%CI: 1.22 to 12.37) compared to those with good oral hygiene. The presence of mouth breathing decreased the rate of recurrence of the disease when compared to the nasal breathing (HR = 0.32; 95%CI: 0.15 to 0.70). Oral health-related behaviors and nasal respiration influenced the rate of dental caries recurrence in individuals with developmental disabilities.

Cross-cultural adaptation of the Brazilian version of the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15).

The dentine hypersensitivity (DH) is able to impair the oral health related quality of life (OHRQoL). However, there isn't any specific validated questionnaire to be used in Brazil. The objective was to adapt and to validate the English version of the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15) for use in Brazil. DHEQ-15 was cross-culturally adapted into the Brazilian-Portuguese language and then validated in a cross-sectional study with 100 participants recruited at a University clinic. Study sample comprised 2 groups: 100 individuals with DH, and 100 individuals without. The instrument was self-administered twice 7 to 10 days apart. The participants answered a global rating of oral health. The psychometric properties of the Brazilian version of DHEQ-15 were verified through internal consistency (Cronbach's α) and test-retest reliability (intraclass correlation coefficient - ICC), convergent (Spearman correlation) and discriminant (Mann-Whitney test) validity. The significance threshold was set at p<0.05. Sample comprised 69 men and 131 women, of mean age 30.4y. The Brazilian DHEQ-15 demonstrated very good internal consistency (α = 0.945). Test-retest reliability revealed excellent reproducibility (ICC = 0.959, p < 0.001). There was statistically significant correlation between the scores obtained on all DHEQ-15 domains and the global rating of oral health (p<0.001). Participants with DH scored significantly higher than those without DH (p<0.001). This study provides evidence supporting the cross-cultural validity of the Brazilian version of DHEQ-15 for use in Brazil.

Relationship between implant stability measurements obtained by insertion torque and resonance frequency analysis: A systematic review.

BACKGROUND: The primary stability of dental implants can be evaluated by insertion torque (IT) and resonance frequency analysis (RFA). OBJECTIVE: Assess the supposed relationship between the IT and RFA. MATERIALS AND METHODS: A systematic review was performed based on the PRISMA. The electronic search was performed in the PubMed, Web of Science, SCOPUS, Cochrane Library electronic, OVID, and Scielo databases. Manual searches were also performed. There was no restrictions regarding year of publication or language. The articles identified were assessed independently by 3 trained researchers. Clinical trials reporting the RFA values by means of implant stability quotient (ISQ) and IT were included. RESULTS: The electronic and manual searches yielded 2017 studies. Twelve studies were included in the systematic review. There was no statistically significant correlation between ISQ and IT (rs = .366; P = .079). The quality of the evidence was downgraded by risk of bias and indirectness; and the certainty of the evidence was low. CONCLUSION: IT and RFA are independent and incomparable methods of measuring primary stability. Is important for clinicians to define only one method of evaluation for each implant.

Laser and Cyanoacrylate for the Treatment of Dentine Hypersensitivity: Survival Analysis and Predictive Factors.

OBJECTIVE: The aim of the present study was to determine how long the effects of laser and cyanoacrylate last when used as treatments for dentine hypersensitivity (DH). In addition, the predictive factors of DH recurrence and the prevalence of DH according to type of tooth were investigated. MATERIALS AND METHODS: Sixty-two patients contributed with 434 sensitive teeth. Two hundred sixteen teeth were randomized to receive laser treatment (wavelength of 795 nm) and 218 received cyanoacrylate treatment. Both treatments were applied three times at intervals of 48 hours. Dentine hypersensitivity was assessed by air stimulus at baseline and 1, 30, 90 and 180 days after treatment by a blinded researcher. Additionally, possible etiologic factors were assessed. The data were analyzed by Kaplan-Meier survival curves and by logistic regression. RESULTS: Both groups had signifi cant reductions in DH. Treatment failure occurred in 276 (63.6%) treated teeth and 158 (36.4%) teeth maintained the result of the treatment until the end of the study (censored teeth). The survival rate at 6 months was 36% for laser treatment, and 36% for cyanoacrylate. There was no signifi cant difference between the survival curves (p = 0.703). Gingival recession and abfraction increased the risk of treatment failure by 2.04 (p = 0.002) and 2.76 (p less than 0.001) times, respectively. CONCLUSIONS: Overall, these two approaches to DH treatment had a survival rate of 36%at 6 months. The most prevalent hypersensitive tooth is the first premolar. Gingival recession and abfraction predict the recurrence of DH irrespective of patient age and sex.

Cross-cultural adaptation of the Brazilian version of the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15)

Abstract The dentine hypersensitivity (DH) is able to impair the oral health related quality of life (OHRQoL). However, there isn't any specific validated questionnaire to be used in Brazil. The objective was to adapt and to validate the English version of the Dentine Hypersensitivity Experience Questionnaire (DHEQ-15) for use in Brazil. DHEQ-15 was cross-culturally adapted into the Brazilian-Portuguese language and then validated in a cross-sectional study with 100 participants recruited at a University clinic. Study sample comprised 2 groups: 100 individuals with DH, and 100 individuals without. The instrument was self-administered twice 7 to 10 days apart. The participants answered a global rating of oral health. The psychometric properties of the Brazilian version of DHEQ-15 were verified through internal consistency (Cronbach's α) and test-retest reliability (intraclass correlation coefficient - ICC), convergent (Spearman correlation) and discriminant (Mann-Whitney test) validity. The significance threshold was set at p<0.05. Sample comprised 69 men and 131 women, of mean age 30.4y. The Brazilian DHEQ-15 demonstrated very good internal consistency (α = 0.945). Test-retest reliability revealed excellent reproducibility (ICC = 0.959, p < 0.001). There was statistically significant correlation between the scores obtained on all DHEQ-15 domains and the global rating of oral health (p<0.001). Participants with DH scored significantly higher than those without DH (p<0.001). This study provides evidence supporting the cross-cultural validity of the Brazilian version of DHEQ-15 for use in Brazil.

Immunohistochemical study of fibronectin, tenascin and type I collagen in tongue and lip carcinomas

AIM: The aim was to compare the immunoexpression of extracellular matrix proteins in squamous cell carcinomas of tongue (SCCTo) and lower lip (SCCLi). METHODS: Eleven SCCTo and 11 SCCLi were selected and examined according to Bryne's method (1998). For immunohistochemical study utilized antibodies to fibronectin, tenascin and type I collagen. Histopathologic and immunohistochemical analysis were performed on the tumor invasive front. RESULTS: All SCCTo were classified in high score malignant grade and all SCCLi in lower score. Fibronectin showed strong immunorreactivity in the peritumoral basement membrane (BM) in 91% of SCCTo and all cases of SCCLi, while in the tumor stroma (TS) all cases of SCCTo and SCCLi had strong intensity. Tenascin had strong expression in BM of 91% cases of SCCTo and 63.4% of SCCLi and in TS had strong expression in 91% cases of SCCTo and 54.6% of SCCLi. Type I collagen demonstrated weak immunoreactivity in the TS of 72.7% cases of SCCTo and 63.4% of SCCLi. CONCLUSION: These results may suggest that the strong expression of fibronectin and tenascin proteins and the weak expression of type I collagen could play a role in the invasive process of oral SCC (AU)

Relationship between implant stability on the abutment and platform level by means of resonance frequency analysis: A cross-sectional study.

Resonance frequency analysis (RFA) has become the main tool used to assess the osseointegration of dental implants. The objective of this study was to verify the relationship between the ISQ values with different prosthetic abutments and with the implant platform. The hypothesis was that ISQ values changes according to the abutment height. Twelve patients were included, whose contribution to the study was 31 dental implants (external hexagon connection implants, 4.1x10 mm). The temporary implant-supported crown and prosthetic components were removed and the following smartpegs were inserted, one at a time: type 1, in the implant platform (G1); type A3, in the microunit component with 1mm transmucosal height (G2) and type A3, in the microunit component with 5mm transmucosal height (G3). In all the smartpegs, RFA measurements were taken on mesial, distal, buccal and lingual surfaces. All evaluations were performed by a single calibrated examiner (ICC = 0.989). Data were analyzed by Friedman and Spearman correlation tests and log-linear marginal regression (p<0.05). The mean age of participants was 52.83 (± 3.77) years. There was statistically significant difference (p<0.001) among the mean ISQ of G1 (88.27 ±5.70); G2 (72.75 ±4.73) and G3 (66.33 ±3.67). There was statistically significant negative correlation between the ISQ and the measurement distance (rs:-0.852; p<0.001; R2:0.553). Measurement distance was significantly associated (p<0.001) with ISQ value in the log-linear regression. The abutment height has a significant impact on resonance frequency analysis measurements. The higher the transmucosal abutment height, the lower the implant stability quotient value. Clinically, the ISQ measured on the abutment cannot be compared with values measured on the implant platform.

Do TMJ symptoms improve and last across time after treatment with red (660 nm) and infrared (790 nm) low level laser treatment (LLLT)? A survival analysis.

OBJECTIVE: Temporomandibular disorder (TMD) is a variety of clinical problems that originate from the area of the temporomandibular joint (TMJ), masticatory muscles, and surrounding tissues. There are different treatment options; however, there is no evidence that low level laser treatment (LLLT) will last about six months. The aim of this study was to determine the survival rate of treatment with red (660 nm) and infrared (790 nm) laser in cases of TMDs. METHODS: In 19 subjects, one side of the face (half face) was randomly selected to receive intervention, in a total of 116 sensitive points. Pain was measured at baseline and time intervals of 24 h, 30, 90, and 180 days after treatment. Laser irradiation with 4 j/cm² in the TMJs and 8 j/cm² in the muscles was used in three sessions. Kaplan-Meier survival analysis and logistic regression were performed. RESULTS: Both treatments showed statistically significant results (p < 0.001). The survival rate for red and infrared laser was 0.24 and 0.30, respectively, at 180 days. Grinding teeth and headache were associated with recurrent pain. DISCUSSION: Both lasers were effective in the treatment of TMD symptoms and had a low survival rate at 180 days.

Influence of Periodontal Parameters on Root Coverage: A Longitudinal Study.

OBJECTIVE: This study aimed to evaluate the effect of initial periodontal clinical parameters on the final outcome of the treatment of periodontal recessions by means of a coronally positioned flap (CPF). MATERIALS AND METHODS: The CPF technique was used in a total of 39 Miller Class I/II gingival recessions of the upper canines and/or premolars. The clinical periodontal parameters evaluated were: probing depth, gingival recession height, gingival recession width, keratinized mucosa, attached keratinized mucosa, flap thickness and free gingival margin thickness. The degree of root coverage was evaluated 6 months and 1 year after the surgery. The data were analyzed by Student's t-test, Mann-Whitney and Pearson's correlation tests, as well as linear regression. RESULTS: A significant reduction in gingival recession height, gingival recession width, keratinized mucosa, and attached keratinized mucosa were observed. A significant negative correlation was found between gingival recession and root coverage percentage at 1 year, and a significant negative correlation between gingival margin thickness and coverage percentage at 1 year. The gingival recession and flap thickness significantly predicted the amount of root coverage. CONCLUSIONS: The initial dimensions of gingival recession and the mucosa thickness were correlated to the percentage of root coverage. The gingival recession width was the major predictor of root coverage.

Estabilidade em implantes dentários: análise da frequência de ressonância e torque de inserção / Stability in dental implants: analysis of resonance frequency and insertion torque

As pesquisas clínicas na área da implantodontia apresentam uma grande dificuldade em relação à avaliação da osseointegração e estabilidade dos implantes. Dessa forma, a análise de frequência de ressonância (AFR) têm se tornado uma das principais ferramentas utilizadas, já que oferece, de forma simples e não invasiva, a possibilidade de se monitorar a estabilidade durante todo o período desejado. Outra medida também bastante usada na prática clínica é o torque de inserção dos implantes. No entanto, essa medida é limitada ao trans-cirúrgico e nos fornece unicamente a estabilidade primária dos implantes, o que a torna mais indicada para avaliação da possibilidade de se submeter à carga imediata. Este estudo apresenta como objetivos avaliar, por meio de um estudo transversal, se os valores do coeficiente de estabilidade do implante (ISQ) são similares em diferentes alturas do componente protético e diretamente na plataforma, quando mensurados por meio da AFR e avaliar por meio de uma revisão sistemática e meta-análise a relação entre o torque de inserção e a AFR, investigando se estes dois instrumentos fornecem avaliações similares da estabilidade primária de em um mesmo implante. Para tal, foi realizado um estudo transversal em 31 implantes osseointegrados com plataforma de hexágono externo, com 4.1 mm de diâmetro e comprimento maior ou igual a 10mm e uma revisão sistemática com ensaios clínicos que reportassem valores de ISQ e torque de inserção. Assim, nossos estudos recomendam que explorar e desenvolver a AFR como método de avaliação da estabilidade implantar deve ser uma busca ainda necessária das pesquisas científicas para melhor compreensão do comportamento dos implantes dentários, nos seus diversos momentos e situações na cavidade oral, bem como determinar um bom nível de estabilidade que consequentemente determinaria uma maior longevidade e funcionalidade dos implantes dentários

Clinical research in the implantology presents a great difficulty regarding the evaluation of the osseointegration and stability of the implants. Thus, resonance frequency analysis (RFA) has become one of the main tools used, since it offers, in a simple and non-invasive way, the possibility of monitoring the stabiblity during the desired period. Another measure also widely used in clinical practice is the insertion torque of the implants. However, this measureis limited to the transsurgical and provides only the primary stability of the implants, which makes it more suitable for evaluation the possibility of undergoing immediate loading. This study aims to evaluate, through a cross-sectional study, whether implant stability coefficient (ISQ) values are similar at different heights...